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In Vitro Evaluation of Cytotoxic Activities of Marketed Herbal Products in Ghana (Including COA Mixture)
Sylvester Languon, MSc1, Isaac Tuffour, MPhil 1,
Emmanuel Ekow Quayson BSc1, Regina Appiah-Opong, PhD1,
and Osbourne Quaye, PhD 1
Conclusions
For the first time, the efficacy and toxicity of some anticancer herbal products on the Ghanaian market have been evaluated. The results show that the herbal products have varied phytochemical profiles, phenolic content, antioxidant activities, and cytotoxic activities. From the IC50 values, the herbal products exerted weak toxicity against the breast, liver, prostate, and blood cancer cell lines tested. Two of the herbal products (MUT and COA) were comparatively potent against the blood cancer cell line. In Ghana, patients who patronize herbal products consume the products chronically.
Chronic intake of the herbal products evaluated in this study could lead to the maintenance of an effective concentration of the active agents, thus immensely contributing to the anticancer activity of the herbal products in vivo. This could, however, have an effect on the toxicity of the herbal products due to the continuous availability of the product in the body.
Although the findings confirm the claims that the selected herbal products are cytotoxic to cancer cells, in vivo studies should be carried out to affirm the potency and toxicities of these herbal products. It is prudent to carry out in vivo studies since liver enzyme activity has an effect on the efficacy and toxicity of consumed herbal products/drugs.
Limitations
The major limitations of the study were the inability to determine some of the plants or plant parts that were used in the preparation of the products due to issues of confidentiality, and there was no normal cell line to compare with the cancer cell lines.
18 Comments
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Please my friend in u s a have hiv please can coa help because my friend in Ghana send it can cure hiv please help my friend for me .Thanks for everything Dr.
Can COA mixture cure prostate enlargement / cancer?
Is this medicine effective
against high blood pressure
It can be used as supportive treatment, kindly use COA MIXTURE for this.
Can COA mixture cure prostate enlargement / cancer?
Coa mixture can support the treatment of Prostate enlargement and any other benign medical condition
Can COA Mixture cure postrate cancer and enlarged postrate?
It helps in the treatment
Can coa fs be used to treat breast cancer or be used by a patient who is undergoing chemotherapy for breast cancer as supportive treatment?
Hi John, Yes it can be used as supportive treatment, but kindly use COA PLUS MIXTURE for this.
Please can COA Mixture cure breast cancer and HIV?
It can be used as supportive treatment, but kindly use COA PLUS MIXTURE
Can COA mixture be beneficial for treating colon cancer?
Yes it can be used as supportive treatment, but kindly use COA PLUS MIXTURE
Please I’m having Chemotherapy for breast cancer 2 can I use coa to boost my immune system?
Yes, buy COA PLUS MIXTURE
Can COA PLUS cure CKS STAGE 2 and Hep B without delta agent with viral load 753.
Give it a trial, it can be of help definately